Details for anatomical structure: bone marrow

Related structures
Hormones
Receptors
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EndoNet ID: ENC00018

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be:

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like

http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000

If the search pattern is unambigious the user is directed to the corresponding detail page.

Synonyms

bone marrow, , Medulla ossium

General information

The tissue filling the cavities of bones, having a stroma of reticular fibers and cells; the soft, spongy tissue found in the centre of most large bones that produces the cellular components of blood: white cells, red cells and platelets

Links to other resources

Cytomer

cy0038433

Larger structures

Substructures

Secreted hormones

Hormone: lipocalin 2
- NGAL was expressed in bone marrow and in tissues that are prone to exposure to microorganisms. [1]
Hormone: VEGF-165
- VEGF, its receptors (VEGFR-1, VEGFR-2) and neuropillin-1 (NRP-1) are expressed at variable levels in bone marrow. [2]
Hormone: IL-11
Hormone: CLC
Hormone: IL-15
Hormone: CXCL11
Hormone: MCP-2
Hormone: IL-7
Hormone: PGI2
Hormone: PGE2
- [3]
Hormone: IL-1F8
Hormone: HCC-1
Hormone: MPIF-1
Hormone: PARC
Hormone: adipsin
Hormone: osteocalcin
Hormone: fibronectin
Hormone: bone sialoprotein 2
Hormone: osteomodulin
Hormone: annexin A2
Hormone: sclerostin
Hormone: WNT10B
Hormone: BAFF
Hormone: defensin alpha 1
Hormone: stem cell growth factor
Hormone: NmU-25
Hormone: GDF-3
Hormone: insulin-like peptide INSL5
Hormone: CD5L
Hormone: proteinase 3
Hormone: elastase-2
Hormone: GnRH-II (Isoform 1)

Receptors

Receptor: PPARgamma1
- mRNA being detectable in spleen, bone marrow, liver, testis, skeletal muscle and brain [4]
Receptor: histamine H4 receptor
Receptor: TLR2
Receptor: M-CSF-1-R
Induced phenotype:
- myeloid cell differentation
Receptor: thrombospondin receptor
Receptor: laminin receptor
Receptor: B-CAM
Receptor: Vascular endothelial growth factor receptor 2
Induced phenotype:
- angiogenesis
  
  Recruitment of circulating endothelial precursors to sites of active angiogenesis is mediated through VEGFR2. [5]
Receptor: Vascular endothelial growth factor receptor 1
Induced phenotype:
- hematopoiesis
  
  Inhibition of VEGFR1, but not VEGFR2, blockes HSC cell cycling, differentiation and hematopoietic recovery after bone marrow suppression. Placental growth factor (PlGF), which signals through VEGFR1, restored early and late phases of hematopoiesis following bone marrow suppression. PlGF promotes recruitment of VEGFR1(+) HSCs from a quiescent to a proliferative bone marrow microenvironment, favoring differentiation, mobilization and reconstitution of hematopoiesis. [6]
Receptor: neuropilin 1
Receptor: ALCAM
Receptor: glypican 1
Receptor: TNFR1
Induced phenotype:
- atherosclerosis
  
  In atherosclerosis, TNF considered to promote plaque growth and progression. [7]
  Bone-marrow derived p55 TNFR promotes atherosclerosis development by enhancing lesional foam-cell formation and by promoting expression of pro-atherosclerotic chemokines, like MCP-1. [8]
Receptor: Sphingosine 1-phosphate receptor 4
Receptor: Probable G-protein coupled receptor 132
Receptor: relaxin receptor 2

Reference

EndoNet

The information resource about the endocrine network in human.

Details for anatomical structure: bone marrow

Synonyms

General information

Links to other resources

Related structures

Larger structures

Substructures

Secreted hormones

Hormone: lipocalin 2 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_0_toolsBtn',{id:'j_idt91:0:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_0_j_idt99',{id:'j_idt91:0:j_idt99',target:'j_idt91:0:toolsBtn',dynamic:true});});

Hormone: VEGF-165 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_1_toolsBtn',{id:'j_idt91:1:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_1_j_idt99',{id:'j_idt91:1:j_idt99',target:'j_idt91:1:toolsBtn',dynamic:true});});

Hormone: IL-11 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_2_toolsBtn',{id:'j_idt91:2:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_2_j_idt99',{id:'j_idt91:2:j_idt99',target:'j_idt91:2:toolsBtn',dynamic:true});});

Hormone: CLC ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_3_toolsBtn',{id:'j_idt91:3:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_3_j_idt99',{id:'j_idt91:3:j_idt99',target:'j_idt91:3:toolsBtn',dynamic:true});});

Hormone: IL-15 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_4_toolsBtn',{id:'j_idt91:4:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_4_j_idt99',{id:'j_idt91:4:j_idt99',target:'j_idt91:4:toolsBtn',dynamic:true});});

Hormone: CXCL11 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_5_toolsBtn',{id:'j_idt91:5:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_5_j_idt99',{id:'j_idt91:5:j_idt99',target:'j_idt91:5:toolsBtn',dynamic:true});});

Hormone: MCP-2 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_6_toolsBtn',{id:'j_idt91:6:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_6_j_idt99',{id:'j_idt91:6:j_idt99',target:'j_idt91:6:toolsBtn',dynamic:true});});

Hormone: IL-7 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_7_toolsBtn',{id:'j_idt91:7:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_7_j_idt99',{id:'j_idt91:7:j_idt99',target:'j_idt91:7:toolsBtn',dynamic:true});});

Hormone: PGI2 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_8_toolsBtn',{id:'j_idt91:8:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_8_j_idt99',{id:'j_idt91:8:j_idt99',target:'j_idt91:8:toolsBtn',dynamic:true});});

Hormone: PGE2 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_9_toolsBtn',{id:'j_idt91:9:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_9_j_idt99',{id:'j_idt91:9:j_idt99',target:'j_idt91:9:toolsBtn',dynamic:true});});

Hormone: IL-1F8 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_10_toolsBtn',{id:'j_idt91:10:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_10_j_idt99',{id:'j_idt91:10:j_idt99',target:'j_idt91:10:toolsBtn',dynamic:true});});

Hormone: HCC-1 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_11_toolsBtn',{id:'j_idt91:11:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_11_j_idt99',{id:'j_idt91:11:j_idt99',target:'j_idt91:11:toolsBtn',dynamic:true});});

Hormone: MPIF-1 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_12_toolsBtn',{id:'j_idt91:12:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_12_j_idt99',{id:'j_idt91:12:j_idt99',target:'j_idt91:12:toolsBtn',dynamic:true});});

Hormone: PARC ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_13_toolsBtn',{id:'j_idt91:13:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_13_j_idt99',{id:'j_idt91:13:j_idt99',target:'j_idt91:13:toolsBtn',dynamic:true});});

Hormone: adipsin ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_14_toolsBtn',{id:'j_idt91:14:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_14_j_idt99',{id:'j_idt91:14:j_idt99',target:'j_idt91:14:toolsBtn',dynamic:true});});

Hormone: osteocalcin ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_15_toolsBtn',{id:'j_idt91:15:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_15_j_idt99',{id:'j_idt91:15:j_idt99',target:'j_idt91:15:toolsBtn',dynamic:true});});

Hormone: fibronectin ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_16_toolsBtn',{id:'j_idt91:16:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_16_j_idt99',{id:'j_idt91:16:j_idt99',target:'j_idt91:16:toolsBtn',dynamic:true});});

Hormone: bone sialoprotein 2 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_17_toolsBtn',{id:'j_idt91:17:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_17_j_idt99',{id:'j_idt91:17:j_idt99',target:'j_idt91:17:toolsBtn',dynamic:true});});

Hormone: osteomodulin ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_18_toolsBtn',{id:'j_idt91:18:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_18_j_idt99',{id:'j_idt91:18:j_idt99',target:'j_idt91:18:toolsBtn',dynamic:true});});

Hormone: annexin A2 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_19_toolsBtn',{id:'j_idt91:19:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_19_j_idt99',{id:'j_idt91:19:j_idt99',target:'j_idt91:19:toolsBtn',dynamic:true});});

Hormone: sclerostin ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_20_toolsBtn',{id:'j_idt91:20:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_20_j_idt99',{id:'j_idt91:20:j_idt99',target:'j_idt91:20:toolsBtn',dynamic:true});});

Hormone: WNT10B ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_21_toolsBtn',{id:'j_idt91:21:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_21_j_idt99',{id:'j_idt91:21:j_idt99',target:'j_idt91:21:toolsBtn',dynamic:true});});

Hormone: BAFF ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_22_toolsBtn',{id:'j_idt91:22:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_22_j_idt99',{id:'j_idt91:22:j_idt99',target:'j_idt91:22:toolsBtn',dynamic:true});});

Hormone: defensin alpha 1 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_23_toolsBtn',{id:'j_idt91:23:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_23_j_idt99',{id:'j_idt91:23:j_idt99',target:'j_idt91:23:toolsBtn',dynamic:true});});

Hormone: stem cell growth factor ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_24_toolsBtn',{id:'j_idt91:24:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_24_j_idt99',{id:'j_idt91:24:j_idt99',target:'j_idt91:24:toolsBtn',dynamic:true});});

Hormone: NmU-25 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_25_toolsBtn',{id:'j_idt91:25:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_25_j_idt99',{id:'j_idt91:25:j_idt99',target:'j_idt91:25:toolsBtn',dynamic:true});});

Hormone: GDF-3 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_26_toolsBtn',{id:'j_idt91:26:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_26_j_idt99',{id:'j_idt91:26:j_idt99',target:'j_idt91:26:toolsBtn',dynamic:true});});

Hormone: insulin-like peptide INSL5 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_27_toolsBtn',{id:'j_idt91:27:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_27_j_idt99',{id:'j_idt91:27:j_idt99',target:'j_idt91:27:toolsBtn',dynamic:true});});

Hormone: CD5L ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_28_toolsBtn',{id:'j_idt91:28:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_28_j_idt99',{id:'j_idt91:28:j_idt99',target:'j_idt91:28:toolsBtn',dynamic:true});});

Hormone: proteinase 3 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_29_toolsBtn',{id:'j_idt91:29:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_29_j_idt99',{id:'j_idt91:29:j_idt99',target:'j_idt91:29:toolsBtn',dynamic:true});});

Hormone: elastase-2 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_30_toolsBtn',{id:'j_idt91:30:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_30_j_idt99',{id:'j_idt91:30:j_idt99',target:'j_idt91:30:toolsBtn',dynamic:true});});

Hormone: GnRH-II (Isoform 1) ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt91_31_toolsBtn',{id:'j_idt91:31:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt91_31_j_idt99',{id:'j_idt91:31:j_idt99',target:'j_idt91:31:toolsBtn',dynamic:true});});

Receptors

Receptor: PPARgamma1 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_0_toolsBtn',{id:'j_idt139:0:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_0_j_idt145',{id:'j_idt139:0:j_idt145',target:'j_idt139:0:toolsBtn',dynamic:true});});

Receptor: histamine H4 receptor ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_1_toolsBtn',{id:'j_idt139:1:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_1_j_idt145',{id:'j_idt139:1:j_idt145',target:'j_idt139:1:toolsBtn',dynamic:true});});

Receptor: TLR2 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_2_toolsBtn',{id:'j_idt139:2:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_2_j_idt145',{id:'j_idt139:2:j_idt145',target:'j_idt139:2:toolsBtn',dynamic:true});});

Receptor: M-CSF-1-R ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_3_toolsBtn',{id:'j_idt139:3:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_3_j_idt145',{id:'j_idt139:3:j_idt145',target:'j_idt139:3:toolsBtn',dynamic:true});});

Induced phenotype:

Receptor: thrombospondin receptor ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_4_toolsBtn',{id:'j_idt139:4:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_4_j_idt145',{id:'j_idt139:4:j_idt145',target:'j_idt139:4:toolsBtn',dynamic:true});});

Receptor: laminin receptor ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_5_toolsBtn',{id:'j_idt139:5:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_5_j_idt145',{id:'j_idt139:5:j_idt145',target:'j_idt139:5:toolsBtn',dynamic:true});});

Receptor: B-CAM ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_6_toolsBtn',{id:'j_idt139:6:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_6_j_idt145',{id:'j_idt139:6:j_idt145',target:'j_idt139:6:toolsBtn',dynamic:true});});

Receptor: Vascular endothelial growth factor receptor 2 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_7_toolsBtn',{id:'j_idt139:7:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_7_j_idt145',{id:'j_idt139:7:j_idt145',target:'j_idt139:7:toolsBtn',dynamic:true});});

Induced phenotype:

Receptor: Vascular endothelial growth factor receptor 1 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_8_toolsBtn',{id:'j_idt139:8:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_8_j_idt145',{id:'j_idt139:8:j_idt145',target:'j_idt139:8:toolsBtn',dynamic:true});});

Induced phenotype:

Receptor: neuropilin 1 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_9_toolsBtn',{id:'j_idt139:9:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_9_j_idt145',{id:'j_idt139:9:j_idt145',target:'j_idt139:9:toolsBtn',dynamic:true});});

Receptor: ALCAM ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_10_toolsBtn',{id:'j_idt139:10:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_10_j_idt145',{id:'j_idt139:10:j_idt145',target:'j_idt139:10:toolsBtn',dynamic:true});});

Receptor: glypican 1 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_11_toolsBtn',{id:'j_idt139:11:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_11_j_idt145',{id:'j_idt139:11:j_idt145',target:'j_idt139:11:toolsBtn',dynamic:true});});

Receptor: TNFR1 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_12_toolsBtn',{id:'j_idt139:12:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_12_j_idt145',{id:'j_idt139:12:j_idt145',target:'j_idt139:12:toolsBtn',dynamic:true});});

Induced phenotype:

Receptor: Sphingosine 1-phosphate receptor 4 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_13_toolsBtn',{id:'j_idt139:13:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_13_j_idt145',{id:'j_idt139:13:j_idt145',target:'j_idt139:13:toolsBtn',dynamic:true});});

Receptor: Probable G-protein coupled receptor 132 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_14_toolsBtn',{id:'j_idt139:14:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_14_j_idt145',{id:'j_idt139:14:j_idt145',target:'j_idt139:14:toolsBtn',dynamic:true});});

Receptor: relaxin receptor 2 ui-buttonPrimeFaces.cw('CommandButton','widget_j_idt139_15_toolsBtn',{id:'j_idt139:15:toolsBtn'}); $(function(){PrimeFaces.cw('OverlayPanel','widget_j_idt139_15_j_idt145',{id:'j_idt139:15:j_idt145',target:'j_idt139:15:toolsBtn',dynamic:true});});

Hormone: lipocalin 2

Hormone: VEGF-165

Hormone: IL-11

Hormone: CLC

Hormone: IL-15

Hormone: CXCL11

Hormone: MCP-2

Hormone: IL-7

Hormone: PGI2

Hormone: PGE2

Hormone: IL-1F8

Hormone: HCC-1

Hormone: MPIF-1

Hormone: PARC

Hormone: adipsin

Hormone: osteocalcin

Hormone: fibronectin

Hormone: bone sialoprotein 2

Hormone: osteomodulin

Hormone: annexin A2

Hormone: sclerostin

Hormone: WNT10B

Hormone: BAFF

Hormone: defensin alpha 1

Hormone: stem cell growth factor

Hormone: NmU-25

Hormone: GDF-3

Hormone: insulin-like peptide INSL5

Hormone: CD5L

Hormone: proteinase 3

Hormone: elastase-2

Hormone: GnRH-II (Isoform 1)

Receptor: PPARgamma1

Receptor: histamine H4 receptor

Receptor: TLR2

Receptor: M-CSF-1-R

Receptor: thrombospondin receptor

Receptor: laminin receptor

Receptor: B-CAM

Receptor: Vascular endothelial growth factor receptor 2

Receptor: Vascular endothelial growth factor receptor 1

Receptor: neuropilin 1

Receptor: ALCAM

Receptor: glypican 1

Receptor: TNFR1

Receptor: Sphingosine 1-phosphate receptor 4

Receptor: Probable G-protein coupled receptor 132

Receptor: relaxin receptor 2