Details for anatomical structure: intestinal smooth muscle cell
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- Related structures
- Hormones
- Receptors
-
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- Top
- Related structures
- Hormones
- Receptors
-
Click to access the toolbox
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Synonyms
intestinal smooth muscle cell, ,Links to other resources
Cytomer | cy0052332 |
Related structures
Larger structures
Substructures
Secreted hormones
-
Hormone: IGF-1
Influenced by:
- IGFBP-5 receptor
in
intestinal_smooth_muscle_cell
- An IGFBP-5 receptor is present in human intestinal smooth muscle cells. Binding of IGFBP-5 to its cognate receptor activates both the p38 MAP kinase and Erk1/2 signaling cascades. Activation of these pathways by IGFBP-5 mediates jointly stimulation of growth and secretion of IGF-I. [1]
- IGFBP-5 receptor
in
intestinal_smooth_muscle_cell
Receptors
-
Receptor: CCK-2
- CCK2R protein has been demonstrated in the stomach muscularis. [2]
Induced phenotype:
- induction of smooth muscle contraction
- The CCK2 receptors mediate an inhibitory effect on human colonic smooth muscle and an inhihitory action of CCK on motor function of human distal colon. [3]
-
Receptor: IGFBP-5 receptor
Influences:
-
Receptor: CCK-1
- The human CCKR1 is expressed at Protein level in the smooth muscle cells of the intestine. [4]
Induced phenotype:
- induction of smooth muscle contraction
- In the human colon, the CCK-induced contraction of the smooth muscle is mediated through the CCK1 receptor. [5]