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Details for anatomical structure: cell of syncytiotrophoblast

EndoNet ID: ENC00137

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Synonyms

cell of syncytiotrophoblast, , Syncytiotrophoblastus

Links to other resources

Cytomer cy0011396

Larger structures

  • placenta
  • circulatory_system__hematopoietic_system
  • parts_of_human_body
  • blood_vessel
  • chorion

Substructures

    Secreted hormones

      Receptors

      • Receptor: transferrin receptor 1

        Induced phenotype:

        • regulation of iron ion transmembrane transport
          • A developing fetus needs a lot of iron, which is transferred across the human placenta. Iron uptake at the apical membrane of the syncytiotrophoblast occurs via TfR-mediated endocytosis of maternal iron. [1]
          • Hemochromatosis factor regulates TfR-mediated iron uptake. TfR and hemochromatosis factor, as well as TfR and divalent metal transporter-1 interact in placental trophoblast cells. [2]
      Reference