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Details for anatomical structure: osteocyte

EndoNet ID: ENC00325

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Synonyms

osteocyte, osseous cell, bone cell, bone corpuscle, Osteocytus

General information

major cell type of mature bone; maintaining the bone matrix;

Links to other resources

Cytomer cy0011282

Larger structures

  • growth_plate
  • brain
  • circulatory_system__hematopoietic_system
  • parts_of_human_body
  • digestive_system
  • cerebellum
  • immune_system
  • blood_vessel
  • bone
  • central_nerve_system_element
  • bone_marrow
  • internal_ear

Substructures

    Secreted hormones

    • Hormone: osteocalcin

    • Hormone: bone sialoprotein 2

    • Hormone: sclerostin

    Receptors

    • Receptor: ER-beta

      Induced phenotype:

      • detection of mechanical stimulus
        • Membrane associated estrogen receptors are essential for the transduction of mecahnical forces into intracellular survival signaling in osteocytes and osteoblast, independent of ligand binding. [1]

    • Receptor: CaSR

      Induced phenotype:

      • bone cell metabolism
        • The CaSR regulates the recruitment, differentiation and survival of osteoblast and osteoclasts. [2]
    Reference