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Details for anatomical structure: gonadotropin releasing hormone neuron

EndoNet ID: ENC00444

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Synonyms

gonadotropin releasing hormone neuron, GnRH neuron,

General information

produces gonadotropin-releasing hormone (GnRH), critical for the neural regulation of fertility.

Links to other resources

Cytomer cy0045839

Larger structures

    Substructures

      Secreted hormones

      • Hormone: GnRH-I

        Influenced by:

        • GPR54
          in gonadotropin_releasing_hormone_neuron
          • Kisspeptins stimulate the secretion of gonadotropins from the pituitary by stimulating the release of GnRH from the forebrain after the activation of GPR54, which is expressed by GnRH neurons. [1]
        • melatonin 1 receptor
          in hypothalamus
          • Potential signal transduction mechanisms involved in the control of GnRH gene expression and secretion by melatonin. [2]
        • NPFF-R1
          in hypothalamus
          • Thus, GnIH/RFRP may also inhibit gonadotropin synthesis and release by inhibiting GnRH neurons [3]

      • Hormone: beta-endorphin

      Receptors

      • Receptor: GPR54

        Influences:

        • GnRH-I
          • Kisspeptins stimulate the secretion of gonadotropins from the pituitary by stimulating the release of GnRH from the forebrain after the activation of GPR54, which is expressed by GnRH neurons. [1]
      Reference