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Details for anatomical structure: posterior raphe nucleus of midbrain

EndoNet ID: ENC00585

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Synonyms

posterior raphe nucleus of midbrain, dorsal raphe nucleus of midbrain, dorsal nucleus of the raphe of midbrain, cell group B7 of midbrain, Nucleus raphes posterior mesencephali

Links to other resources

Cytomer cy0006189

Larger structures

  • brain
  • circulatory_system__hematopoietic_system
  • brain_stem
  • central_nerve_system_element
  • tegmentum_of_mesencephalon

Substructures

  • glial_cell_of_central_nervous_system
  • astrocyte
  • microglial_cell_in_central_nervous_system
  • oligodendrocyte
  • bergmann_glia

Secreted hormones

  • Hormone: serotonin

    Influenced by:

    • 5-HT-1A
      in posterior_raphe_nucleus_of_midbrain
      • The activation of somatodendritic autoreceptors inhibit the electric activity of serotoninergic neurons, thereby reducing serotonin release and neurotransmission. [1]

Receptors

  • Receptor: 5-HT-1A

    • Somatodendritic 5-HT-1A autoreceptors located on the 5-hydroxytryptaminergic neurones in the dorsal raphe nucleus. [2]
    • 5-HT-1A activation results in the opening of the K+ channels, thereby producing membrane hyperpolarization and a decrease in membrane resistance. [3]
    • The activation of somatodendritic autoreceptors inhibit the electric activity of serotoninergic neurons, thereby reducing serotonin release and neurotransmission. [1]

    Influences:

    • serotonin
      • The activation of somatodendritic autoreceptors inhibit the electric activity of serotoninergic neurons, thereby reducing serotonin release and neurotransmission. [1]
Reference