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Details for messenger / hormone: T3

EndoNet ID: ENH00056

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Synonyms

  • T3
  • triiodothyronine
  • 3,3´,5-triiodo-L-thyronine
  • L-3,5,3'-triiodothyronine
  • 3,5,3'-triiodothyronine
  • liothyronine
  • 3,5,3'-L-triiodo-L-thyronine

General information

Classification

Hormone function

  • metabolism
    • cell metabolism

    Chemical classification

    • hormone
      • not genome-encoded
        • amino acids
          • tyrosine-derived
            • thyroid hormones

      Composition

      KEGG C02465

      Links to other resources

      • Anatomical structure: thyroid_gland

        Influenced by:

        • thyroid stimulating hormone receptor
          in thyroid_gland

      Targets

      CellTHRA1THRB1thyroid hormone receptorthyroid hormone receptor beta 2
      brain Present
      		Present
      chondrocyte Present
      		Present
      		Present
      Phenotypes
      • chondrocyte hypertrophy
      		Present
      hepatocyte Present
      Influences
      • ↑ APOA5
      		Present
      Influences
      • ↑ APOA5
      internal ear Present
      liver Present
      lung Present
      		Present
      macrophage Present
      		Present
      		Present
      osteoblast Present
      		Present
      		Present
      paraventricular nucleus of hypothalamus Present
      Influences
      • ↓ TRH
      		Present
      Influences
      • ↓ TRH
      		Present
      Influences
      • ↓ TRH
      • ↓ Oxytocin-Neurophysin 1
      • ↑ antidiuretic hormone
      pituitary gland of diencephalon Present
      retina Present
      thymic epithelial cell Present
      Influences
      • ↑ Thymulin
      thyroid gland Present
      Phenotypes
      • generalized autosomal-recessive thyroid hormone resistance
      		Present
      Phenotypes
      • Toxic multinodular goitre
      • Hyperthyroidism
      • Hypothyroidism
      Reference