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Details for messenger / hormone: SAA3

EndoNet ID: ENH00202

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Synonyms

  • SAA3P
  • putative serum amyloid A-3 protein
  • SAA3
  • serum amyloid A3

General information

  • Expression and release of SAA3 occurs in murine adipocytes, and this is up regulated under hyperglycaemic conditions. [1]
  • Serum amyloid A (SAA) is a major acute-phase plasma protein synthesized by the liver. [2]
  • Predominant extrahepatic expression. [2]
  • Function: proposed mediators of inflammation and chronic hyperglycemia, thus they might link inflammation to the development of obesity. [3]

Classification

Hormone function

  • immune response
    • activation
    • metabolism

    Chemical classification

    Composition

    Sequence 
    MKLSTGIIF CSLVLGVSS QGWLTFLKA 
AGQGAKDMW RAYSDMKEA NYKKSDKYF 
HARGNYDAV QRGPGGVWA TEVISDARE 
NVQRLTGDH AEDSLAGQA TNKWGQSGK 
DPNHFRPAG LPEKY
    UniProt P22614

    Links to other resources

    UniProt P22614
    Ensembl ENST00000278207

    • Anatomical structure: fat_cell

      • Expression and release of SAA3 occurs in murine adipocytes. [1]

    Targets

    Cell
    No records found.
    Reference