Status
Please wait ...

Details for messenger / hormone: RBP4

EndoNet ID: ENH00238

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be: 

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like 

http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000
If the search pattern is unambigious the user is directed to the corresponding detail page.

Synonyms

  • retinol binding protein 4
  • plasma retinol-binding protein
  • RBP4
  • retinol-binding protein 4

General information

  • Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. [1]
  • RBP4 is an adipocyte-derived 'signal' that may contribute to the pathogenesis of type 2 diabetes. [1]
  • RBP4 is the only specific transport protein for retinol (vitamin A) in the circulation, and to date, its only known function is to deliver retinol to tissues. [1]
  • Adipocytes store retinoid and synthesize and secrete RBP. [2]

Classification

Hormone function

  • metabolism
    • nutrient supply

    Chemical classification

    • hormone
      • genome-encoded
        • lipocalins/fatty acid-binding proteins

      Links to other resources

      UniProt P02753
      Ensembl ENST00000371467
      KEGG hsa:5950

      • Anatomical structure: adipose_tissue

        • RBP4 is an adipocyte-derived 'signal' that may contribute to the pathogenesis of type 2 diabetes. [1]

      • Anatomical structure: fat_cell

        • RBP4 is an adipocyte-derived 'signal' that may contribute to the pathogenesis of type 2 diabetes. [1]

      Targets

      Cell
      No records found.
      Reference