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Details for messenger / hormone: metallothionein

EndoNet ID: ENH00240

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Synonyms

  • Metallothionein-IA
  • Metallothionein-1A
  • metallothionein
  • metallothionein 1A
  • MT1A

General information

  • Metallothionein is a low molecular-weight cysteine-rich, stress-response and metal-binding protein expressed in human adipose tissue. [1]
  • Metallothionein is a metal-binding and stress-response protein which may have an antioxidant role. [2]
  • Metallothionein is a novel secretory product of the differentiated white adipocyte and its production is regulated particularly by glucocorticoids and through a cAMP-dependent pathway. [3]
  • Metallothionein is expressed in adipocytes of brown fat and is induced by catecholamines and zinc. [4]

Classification

Hormone function

  • CNS function
    • stress response

    Chemical classification

    Composition

    processed

    Sequence 
    MDPNCSCAT GGSCTCTGS CKCKECKCT 
SCKKSCCSC CPMSCAKCA QGCICKGAS 
EKCSCCA

    Links to other resources

    UniProt P04731
    Ensembl ENST00000443255
    KEGG hsa:4489

    • Anatomical structure: adipose_tissue

    • Anatomical structure: fat_cell

      • Metallothionein is a low molecular-weight cysteine-rich, stress-response and metal-binding protein expressed in human adipose tissue. [1]

    Targets

    Cell
    No records found.
    Reference