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Details for messenger / hormone: neurotrophin-4

EndoNet ID: ENH00268

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Synonyms

  • NT-5
  • neutrophic factor 4
  • neutrophic factor 5
  • neurotrophin-4
  • NT-4
  • NTF5
  • NT5
  • NT4
  • NTF4
  • neurotrophin 4
  • neurotrophin-5
  • neurotrophin 5

General information

  • NT-4/5, like BDNF, promotes oocyte nuclear maturation. [1]
  • Both BDNF and NT-4/5 are ligands for the Trk B receptor. [1]

Classification

Hormone function

  • development and growth
    • embryogenesis

    Chemical classification

    • hormone
      • genome-encoded
        • cytokines

    Composition

    Sequence
    GVSETAPAS RRGELAVCD AVSGWVTDR 
    RTAVDLRGR EVEVLGEVP AAGGSPLRQ 
    YFFETRCKA DNAEEGGPG AGGGGCRGV 
    DRRHWVSEC KAKQSYVRA LTADAQGRV 
    GWRWIRIDT ACVCTLLSR TGRA

    Links to other resources

    UniProt P34130
    Ensembl ENST00000301411
    KEGG hsa:4909

      Targets

      CellNGF receptortrkB
      dorsal root ganglion Present
      Phenotypes
      • regulation of feeding behavior
      Reference