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Details for messenger / hormone: NRG1-beta1

EndoNet ID: ENH00318

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Synonyms

  • glial growth factor
  • sensory and motor neuron-derived factor
  • acetylcholine receptor-inducing activity
  • breast cancer cell differentiation factor p45
  • Heregulin
  • neu differentiation factor
  • pro-neuregulin-1, membrane-bound isoform
  • NRG1-beta1
  • heregulin beta-1
  • HRG-beta1

General information

Classification

Hormone function

  • development and growth
    • growth stimulation

    Chemical classification

    • hormone
      • genome-encoded
        • cytokines
          • neuregulin-family

      Composition

      isoform 6, sequence

      Sequence
      MSERKEGRG KGKGKKKER GSGKKPESA 
      AGSQSPALP PRLKEMKSQ ESAAGSKLV 
      LRCETSSEY SSLRFKWFK NGNELNRKN 
      KPQNIKIQK KPGKSELRI NKASLADSG 
      EYMCKVISK LGNDSASAN ITIVESNEI 
      ITGMPASTE GAYVSSESP IRISVSTEG 
      ANTSSSTST STTGTSHLV KCAEKEKTF 
      CVNGGECFM VKDLSNPSR YLCKCPNEF 
      TGDRCQNYV MASFYKHLG IEFMEAEEL 
      YQKRVLTIT GICIALLVV GIMCVVAYC 
      KTKKQRKKL HDRLRQSLR SERNNMMNI 
      ANGPHHPNP PPENVQLVN QYVSKNVIS 
      SEHIVEREA ETSFSTSHY TSTAHHSTT 
      VTQTPSHSW SNGHTESIL SESHSVIVM 
      SSVENSRHS SPTGGPRGR LNGTGGPRE 
      CNSFLRHAR ETPDSYRDS PHSERYVSA 
      MTTPARMSP VDFHTPSSP KSPPSEMSP 
      PVSSMTVSM PSMAVSPFM EEERPLLLV 
      TPPRLREKK FDHHPQQFS SFHHNPAHD 
      SNSLPASPL RIVEDEEYE TTQEYEPAQ 
      EPVKKLANS RRAKRTKPN GHIANRLEV 
      DSNTSSQSS NSESETEDE RVGEDTPFL 
      GIQNPLAAS LEATPAFRL ADSRTNPAG 
      RFSTQEEIQ ARLSSVIAN QDPIAV

      Links to other resources

      UniProt Q02297-6
      Ensembl ENST00000287840
      KEGG hsa:3084

        Targets

        CellErbB3ErbB4
        No records found.
        Reference