Status
Please wait ...

Details for messenger / hormone: gremlin-2

EndoNet ID: ENH00512

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be: 

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like 

http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000
If the search pattern is unambigious the user is directed to the corresponding detail page.

Synonyms

  • CKTSF1B2
  • DAN domain family member 3
  • gremlin-2
  • cysteine knot superfamily 1, BMP antagonist 2
  • protein related to DAN and cerberus
  • DAND3
  • PRDC

General information

  • GREMLIN and DANTE are secreted antagonists for BMPs and SLITs. [1]
  • It binds and blocks the activity of BMP-2 and BMP-4. [2]
  • Antagonist of BMP.

Classification

Hormone function

  • development and growth
    • embryogenesis

    Chemical classification

    Links to other resources

    UniProt Q9H772
    Ensembl ENST00000318160
    KEGG hsa:64388

    • Anatomical structure: osteoblast

    • Anatomical structure: chondrocyte

    • Anatomical structure: ovary

    • Anatomical structure: neuron

    Targets

    Cell
    No records found.
    Reference