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Details for messenger / hormone: crossveinless-2

EndoNet ID: ENH00518

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Synonyms

  • crossveinless-2
  • protein crossveinless-2
  • crossveinless 2
  • BMP-binding endothelial regulator protein
  • bone morphogenetic protein-binding endothelial cell precursor-derived regulator
  • crossveinless-2 protein
  • hCV2
  • BMPER
  • hCV-2

General information

  • Human crossveinless-2 is an inhibitor of bone morphogenetic proteins. [1]
  • hCV-2 is secreted as an 80 kDa protein. [1]

Classification

Hormone function

  • development and growth
    • growth inhibition
      • embryogenesis

      Chemical classification

      Composition

      BMP-binding endothelial regulator protein

      Sequence
      SSFLTGSVA KCENEGEVL QIPFITDNP 
      CIMCVCLNK EVTRKREKC PVLSRDCAL 
      AIKQRGACC EQCKGCTYE GNTYNSSFK 
      WQSPAEPCV LRQCQEGVV TESGVRCVV 
      HCKNPLEHL GMCCPTCPG CVFEGVQYQ 
      EGEEFQPEG SKCTKCSCT GGRTQCVRE 
      VCPILSCPQ HLSHIPPGQ CCPKCLGQR 
      KVFDLPFGS CLFRSDVYD NGSSFLYDN 
      CTACTCRDS TVVCKRKCS HPGGCDQGQ 
      EGCCEECLL RVPPEDIKV CKFGNKIFQ 
      DGEMWSSIN CTICACVKG RTECRNKQC 
      IPISSCPQG KILNRKGCC PICTEKPGV 
      CTVFGDPHY NTFDGRTFN FQGTCQYVL 
      TKDCSSPAS PFQVLVKND ARRTRSFSW 
      TKSVELVLG ESRVSLQQH LTVRWNGSR 
      IALPCRAPH FHIDLDGYL LKVTTKAGL 
      EISWDGDSF VEVMAAPHL KGKLCGLCG 
      NYNGHKRDD LIGGDGNFK FDVDDFAES 
      WRVESNEFC NRPQRKPVP ELCQGTVKV 
      KLRAHRECQ KLKSWEFQT CHSTVDYAT 
      FYRSCVTDM CECPVHKNC YCESFLAYT 
      RACQREGIK VHWEPQQNC AATQCKHGA 
      VYDTCGPGC IKTCDNWNE IGPCNKPCV 
      AGCHCPANL VLHKGRCIK PVLCPQR
      UniProt Q8N8U9

      Links to other resources

      UniProt Q8N8U9
      Ensembl ENST00000426693
      KEGG hsa:168667
      • Anatomical structure: brain

      • Anatomical structure: chondrocyte

      • Anatomical structure: lung

      • Anatomical structure: chondrocyte

      Targets

      Cell
      No records found.
      Reference