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Details for messenger / hormone: katacalcin

EndoNet ID: ENH00617

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Synonyms

  • katacalcin
  • Calcitonin
  • calcitonin carboxyl-terminal peptide
  • CCP
  • PDN-21
  • KC

General information

  • Katacalcin is involved in both plasma calcium regulation and skeletal maintenance and thus proves useful in the treatment of bone disease. [1]
  • Katacalcin is a potent plasma calcium-lowering peptide. [2]
  • Katacalcin belongs to a small family of polypeptides that are encoded by the calc-1 gene and also include calcitonin (CT) and procalcitonin NH2-terminal cleavage peptide (N-ProCT). [3]
  • KC regulates human CD14+ peripheral blood mononuclear cells migration via signaling events involving protein kinase A-dependent cAMP pathways. [3]

Classification

Hormone function

  • homeostasis
    • ion flow control

    Chemical classification

    • hormone
      • genome-encoded
        • calcitonin family

      Composition

      katacalcin

      Sequence 
      DMSSDLERD HRPHVSMPQ NAN
      UniProt P01258-1

      Links to other resources

      UniProt P01258
      Ensembl ENST00000396372
      KEGG hsa:796

      • Anatomical structure: thyroid_gland

      • Anatomical structure: parafollicular_cell

      Targets

      Cell
      No records found.
      Reference