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Details for messenger / hormone: uteroglobin-related protein 2

EndoNet ID: ENH00672

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Synonyms

  • high in normal 1
  • uteroglobin-related protein 2
  • secretoglobin family 3A member 1
  • SCGB3A1
  • PnSP-2
  • UGRP2
  • HIN1
  • PNSP2
  • cytokine HIN-1
  • high in normal-1
  • pneumo secretory protein 2
  • HIN-1

General information

  • The HIN-1 gene encoding a small, secreted protein is silenced due to methylation in a substantial fraction of breast, prostate, lung, and pancreatic carcinomas, suggesting a potential tumor suppressor function. [1]
  • HIN-1 is a potent inhibitor of anchorage-dependent and anchorage-independent cell growth, cell migration, and invasion. [1]

Classification

Hormone function

  • development and growth
    • growth inhibition

    Chemical classification

    Composition

    Uteroglobin-related protein 2.

    Sequence 
    FLVGSAKPV AQPVAALES AAEAGAGTL 
ANPLGTLNP LKLLLSSLG IPVNHLIEG 
SQKCVAELG PQAVGAVKA LKALLGALT 
VFG
    UniProt Q96QR1

    Links to other resources

    UniProt Q96QR1
    Ensembl ENST00000292641
    KEGG hsa:92304

      Targets

      CellMARCO
      No records found.
      Reference