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Details for messenger / hormone: mucin-2

EndoNet ID: ENH00708

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Synonyms

  • mucin-2
  • intestinal mucin-2
  • MUC2

General information

  • Coats the epithelia of the intestines, airways and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. [1]

Classification

Hormone function

  • homeostasis
    • pulmonary control
    • immune response
      • activation

      Chemical classification

      Composition

      Sequence 
      SELQTEGRT RYHGRNVCS TWGNFHYKT 
FDGDVFRFP GLCDYNFAS DCRGSYKEF 
AVHLKRGPG QAEAPAGVE SILLTIKDD 
TIYLTRHLA VLNGAVVST PHYSPGLLI 
EKSDAYTKV YSRAGLTLM WNREDALML 
ELDTKFRNH TCGLCGDYN GLQSYSEFL 
SDGVLFSPL EFGNMQKIN QPDVVCEDP 
EEEVAPASC SEHRAECER LLTAEAFAD 
CQDLVPLEP YLRACQQDR CRCPGGDTC 
VCSTVAEFS RQCSHAGGR PGNWRTATL 
CPKTCPGNL VYLESGSPC MDTCSHLEV 
SSLCEEHRM DGCFCPEGT VYDDIGDSG 
CVPVSQCHC RLHGHLYTP GQEITNDCE 
QCVCNAGRW VCKDLPCPG TCALEGGSH 
ITTFDGKTY TFHGDCYYV LAKGDHNDS 
YALLGELAP CGSTDKQTC LKTVVLLAD 
KKKNAVVFK SDGSVLLNQ LQVNLPHVT 
ASFSVFRPS SYHIMVSMA IGVRLQVQL 
APVMQLFVT LDQASQGQV QGLCGNFNG 
LEGDDFKTA SGLVEATGA GFANTWKAQ 
STCHDKLDW LDDPCSLNI ESANYAEHW 
CSLLKKTET PFGRCHSAV DPAEYYKRC 
KYDTCNCQN NEDCLCAAL SSYARACTA 
KGVMLWGWR EHVCNKDVG SCPNSQVFL 
YNLTTCQQT CRSLSEADS HCLEGFAPV 
DGCGCPDHT FLDEKGRCV PLAKCSCYH 
RGLYLEAGD VVVRQEERC VCRDGRLHC 
RQIRLIGQS CTAPKIHMD CSNLTALAT 
SKPRALSCQ TLAAGYYHT ECVSGCVCP 
DGLMDDGRG GCVVEKECP CVHNNDLYS 
SGAKIKVDC NTCTCKRGR WVCTQAVCH 
GTCSIYGSG HYITFDGKY YDFDGHCSY 
VAVQDYCGQ NSSLGSFSI ITENVPCGT 
TGVTCSKAI KIFMGRTEL KLEDKHRVV 
IQRDEGHHV AYTTREVGQ YLVVESSTG 
IIVIWDKRT TVFIKLAPS YKGTVCGLC 
GNFDHRSNN DFTTRDHMV VSSELDFGN 
SWKEAPTCP DVSTNPEPC SLNPHRRSW 
AEKQCSILK SSVFSICHS KVDPKPFYE 
ACVHDSCSC DTGGDCECF CSAVASYAQ 
ECTKEGACV FWRTPDLCP IFCDYYNPP 
HECEWHYEP CGNRSFETC RTINGIHSN 
ISVSYLEGC YPRCPKDRP IYEEDLKKC 
VTADKCGCY VEDTHYPPG ASVPTEETC 
KSCVCTNSS QVVCRPEEG KILNQTQDG 
AFCYWEICG PNGTVEKHF NICSITTRP 
STLTTFTTI TLPTTPTSF TTTTTTTTP 
TSSTVLSTT PKLCCLWSD WINEDHPSS 
GSDDGDREP FDGVCGAPE DIECRSVKD 
PHLSLEQHG QKVQCDVSV GFICKNEDQ 
FGNGPFGLC YDYKIRVNC CWPMDKCIT 
TPSPPTTTP SPPPTTTTT LPPTTTPSP 
PTTTTTTPP PTTTPSPPI TTTTTPLPT 
TTPSPPIST TTTPPPTTT PSPPTTTPS 
PPTTTPSPP TTTTTTPPP TTTPSPPMT 
TPITPPAST TTLPPTTTP SPPTTTTTT 
PPPTTTPSP PTTTPITPP TSTTTLPPT 
TTPSPPPTT TTTPPPTTT PSPPTTTTP 
SPPTITTTT PPPTTTPSP PTTTTTTPP 
PTTTPSPPT TTPITPPTS TTTLPPTTT 
PSPPPTTTT TPPPTTTPS PPTTTTPSP 
PITTTTTPP PTTTPSSPI TTTPSPPTT 
TMTTPSPTT TPSSPITTT TTPSSTTTP 
SPPPTTMTT PSPTTTPSP PTTTMTTLP 
PTTTSSPLT TTPLPPSIT PPTFSPFST 
TTPTTPCVP LCNWTGWLD SGKPNFHKP 
GGDTELIGD VCGPGWAAN ISCRATMYP 
DVPIGQLGQ TVVCDVSVG LICKNEDQK 
PGGVIPMAF CLNYEINVQ CCECVTQPT 
TMTTTTTEN PTPPTTTPI TTTTTVTPT 
PTPTGTQTP TTTPITTTT TVTPTPTPT 
GTQTPTTTP ITTTTTVTP TPTPTGTQT 
PTTTPITTT TTVTPTPTP TGTQTPTTT 
PITTTTTVT PTPTPTGTQ TPTTTPITT 
TTTVTPTPT PTGTQTPTT TPITTTTTV 
TPTPTPTGT QTPTTTPIT TTTTVTPTP 
TPTGTQTPT TTPITTTTT VTPTPTPTG 
TQTPTTTPI TTTTTVTPT PTPTGTQTP 
TTTPITTTT TVTPTPTPT GTQTPTTTP 
ITTTTTVTP TPTPTGTQT PTTTPITTT 
TTVTPTPTP TGTQTPTTT PITTTTTVT 
PTPTPTGTQ TPTTTPITT TTTVTPTPT 
PTGTQTPTT TPITTTTTV TPTPTPTGT 
QTPTTTPIT TTTTVTPTP TPTGTQTPT 
TTPITTTTT VTPTPTPTG TQTPTTTPI 
TTTTTVTPT PTPTGTQTP TTTPITTTT 
TVTPTPTPT GTQTPTTTP ITTTTTVTP 
TPTPTGTQT PTTTPITTT TTVTPTPTP 
TGTQTPTTT PITTTTTVT PTPTPTGTQ 
TPTTTPITT TTTVTPTPT PTGTQTPTT 
TPITTTTTV TPTPTPTGT QTPTTTPIT 
TTTTVTPTP TPTGTQTPT TTPITTTTT 
VTPTPTPTG TQTPTTTPI TTTTTVTPT 
PTPTGTQTP TTTPITTTT TVTPTPTPT 
GTQTPTTTP ITTTTTVTP TPTPTGTQT 
PTTTPITTT TTVTPTPTP TGTQTPTTT 
PITTTTTVT PTPTPTGTQ TPTTTPITT 
TTTVTPTPT PTGTQTPTT TPITTTTTV 
TPTPTPTGT QTPTTTPIT TTTTVTPTP 
TPTGTQTPT TTPITTTTT VTPTPTPTG 
TQTPTTTPI TTTTTVTPT PTPTGTQTP 
TTTPITTTT TVTPTPTPT GTQTPTTTP 
ITTTTTVTP TPTPTGTQT PTTTPITTT 
TTVTPTPTP TGTQTPTTT PITTTTTVT 
PTPTPTGTQ TPTTTPITT TTTVTPTPT 
PTGTQTPTT TPITTTTTV TPTPTPTGT 
QTPTTTPIT TTTTVTPTP TPTGTQTPT 
TTPITTTTT VTPTPTPTG TQTPTTTPI 
TTTTTVTPT PTPTGTQTP TTTPITTTT 
TVTPTPTPT GTQTPTTTP ITTTTTVTP 
TPTPTGTQT PTTTPITTT TTVTPTPTP 
TGTQTPTTT PITTTTTVT PTPTPTGTQ 
TPTTTPITT TTTVTPTPT PTGTQTPTT 
TPITTTTTV TPTPTPTGT QTPTTTPIT 
TTTTVTPTP TPTGTQTPT TTPITTTTT 
VTPTPTPTG TQTPTTTPI TTTTTVTPT 
PTPTGTQTP TTTPITTTT TVTPTPTPT 
GTQTPTTTP ITTTTTVTP TPTPTGTQT 
PTTTPITTT TTVTPTPTP TGTQTPTTT 
PITTTTTVT PTPTPTGTQ TPTTTPITT 
TTTVTPTPT PTGTQTPTT TPITTTTTV 
TPTPTPTGT QTPTTTPIT TTTTVTPTP 
TPTGTQTPT TTPITTTTT VTPTPTPTG 
TQTPTTTPI TTTTTVTPT PTPTGTQTP 
TTTPITTTT TVTPTPTPT GTQTPTTTP 
ITTTTTVTP TPTPTGTQT PTTTPITTT 
TTVTPTPTP TGTQTPTTT PITTTTTVT 
PTPTPTGTQ TPTTTPITT TTTVTPTPT 
PTGTQTPTT TPITTTTTV TPTPTPTGT 
QTPTTTPIT TTTTVTPTP TPTGTQTPT 
TTPITTTTT VTPTPTPTG TQTPTTTPI 
TTTTTVTPT PTPTGTQTP TTTPITTTT 
TVTPTPTPT GTQTPTTTP ITTTTTVTP 
TPTPTGTQT PTTTPITTT TTVTPTPTP 
TGTQTPTTT PITTTTTVT PTPTPTGTQ 
TPTTTPITT TTTVTPTPT PTGTQTPTT 
TPITTTTTV TPTPTPTGT QTPTTTPIT 
TTTTVTPTP TPTGTQTPT TTPITTTTT 
VTPTPTPTG TQTPTTTPI TTTTTVTPT 
PTPTGTQTP TTTPITTTT TVTPTPTPT 
GTQTPTTTP ITTTTTVTP TPTPTGTQT 
PTTTPITTT TTVTPTPTP TGTQTPTTT 
PITTTTTVT PTPTPTGTQ TPTTTPITT 
TTTVTPTPT PTGTQTPTT TPITTTTTV 
TPTPTPTGT QTPTTTPIT TTTTVTPTP 
TPTGTQTPT TTPITTTTT VTPTPTPTG 
TQTPTTTPI TTTTTVTPT PTPTGTQTP 
TTTPITTTT TVTPTPTPT GTQTPTTTP 
ITTTTTVTP TPTPTGTQT PTTTPITTT 
TTVTPTPTP TGTQTPTTT PITTTTTVT 
PTPTPTGTQ TPTTTPITT TTTVTPTPT 
PTGTQTPTT TPITTTTTV TPTPTPTGT 
QTPTTTPIT TTTTVTPTP TPTGTQTPT 
TTPITTTTT VTPTPTPTG TQTPTTTPI 
TTTTTVTPT PTPTGTQTG PPTHTSTAP 
IAELTTSNP PPESSTPQT SRSTSSPLT 
ESTTLLSTL PPAIEMTST APPSTPTAP 
TTTSGGHTL SPPPSTTTS PPGTPTRGT 
TTGSSSAPT PSTVQTTTT SAWTPTPTP 
LSTPSIIRT TGLRPYPSS VLICCVLND 
TYYAPGEEV YNGTYGDTC YFVNCSLSC 
TLEFYNWSC PSTPSPTPT PSKSTPTPS 
KPSSTPSKP TPGTKPPEC PDFDPPRQE 
NETWWLCDC FMATCKYNN TVEIVKVEC 
EPPPMPTCS NGLQPVRVE DPDGCCWHW 
ECDCYCTGW GDPHYVTFD GLYYSYQGN 
CTYVLVEEI SPSVDNFGV YIDNYHCDP 
NDKVSCPRT LIVRHETQE VLIKTVHMM 
PMQVQVQVN RQAVALPYK KYGLEVYQS 
GINYVVDIP ELGVLVSYN GLSFSVRLP 
YHRFGNNTK GQCGTCTNT TSDDCILPS 
GEIVSNCEA AADQWLVND PSKPHCPHS 
SSTTKRPAV TVPGGGKTT PHKDCTPSP 
LCQLIKDSL FAQCHALVP PQHYYDACV 
FDSCFMPGS SLECASLQA YAALCAQQN 
ICLDWRNHT HGACLVECP SHREYQACG 
PAEEPTCKS SSSQQNNTV LVEGCFCPE 
GTMNYAPGF DVCVKTCGC VGPDNVPRE 
FGEHFEFDC KNCVCLEGG SGIICQPKR 
CSQKPVTHC VEDGTYLAT EVNPADTCC 
NITVCKCNT SLCKEKPSV CPLGFEVKS 
KMVPGRCCP FYWCESKGV CVHGNAEYQ 
PGSPVYSSK CQDCVCTDK VDNNTLLNV 
IACTHVPCN TSCSPGFEL MEAPGECCK 
KCEQTHCII KRPDNQHVI LKPGDFKSD 
PKNNCTFFS CVKIHNQLI SSVSNITCP 
NFDASICIP GSITFMPNG CCKTCTPRN 
ETRVPCSTV PVTTEVSYA GCTKTVLMN 
HCSGSCGTF VMYSAKAQA LDHSCSCCK 
EEKTSQREV VLSCPNGGS LTHTYTHIE 
SCQCQDTVC GLPTGTSRR ARRSPRHLG 
SG

      Links to other resources

      UniProt Q02817
      Ensembl ENST00000359061
      KEGG hsa:4583

      • Anatomical structure: epithelial_cell_with_microvilli

        Influenced by:

        • EGFR isoform a
          in epithelial_cell_with_microvilli
          • PAFR transduces the signal to EGFR via ADAM10-dependent proteolysis of transmembrane HB-EGF. [2]

      • Anatomical structure: colon

      • Anatomical structure: bronchi

      • Anatomical structure: gallbladder

      • Anatomical structure: small_intestine

      • Anatomical structure: cervix_of_uterus

      Targets

      Cell
      No records found.
      Reference