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Details for messenger / hormone: cathelicidin

EndoNet ID: ENH00712

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Synonyms

  • FALL-39 peptide antibiotic
  • cathelicidin antimicrobial peptide
  • cathelicidin
  • 18 kDa cationic antimicrobial protein
  • CAP-18
  • hCAP-18

General information

Classification

Hormone function

  • immune response
    • activation

    Chemical classification

    • hormone
      • genome-encoded
        • antimicrobial peptides

    Links to other resources

    UniProt P49913
    Ensembl ENST00000296435
    KEGG hsa:820

    • Anatomical structure: keratinocyte

      • Keratinocyte synthesis and processing of cathelicidin contribute to skin innate immunity by forming a direct antimicrobial defense barrier that supplements circulating immune cells. [1]

      Influenced by:

      • VDR
        in keratinocyte
        • We provide evidence that the CAMP gene is a direct target of the transcription factor vitamin D receptor (VDR) that mediates the strong up-regulation of CAMP in response to treatment of cells with vitamin D3 [2]

    • Anatomical structure: neutrophil_granulocyte

    Targets

    Cell
    No records found.
    Reference