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Details for messenger / hormone: VEGF-145

EndoNet ID: ENH00758

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Synonyms

  • vascular permeability factor
  • vascular endothelial growth factor A
  • isoform 145 AA of VEGF-A
  • VEGF145
  • VEGF(145)
  • VEGF-145

General information

  • VEGF145 is a secreted vascular endothelial growth factor isoform that binds to extracellular matrix. [1]

Classification

Hormone function

  • development and growth
    • growth stimulation

    Chemical classification

    • hormone
      • genome-encoded
        • cytokines
          • PDGF/VEGF growth factor family

      Composition

      Sequence 
      APMAEGGGQ NHHEVVKFM DVYQRSYCH 
PIETLVDIF QEYPDEIEY IFKPSCVPL 
MRCGGCCND EGLECVPTE ESNITMQIM 
RIKPHQGQH IGEMSFLQH NKCECRPKK 
DRARQEKKS VRGKGKGQK RKRKKSRYK 
SWSVCDKPR R

      Links to other resources

      UniProt P15692-6
      Ensembl ENST00000372055
      KEGG hsa:7422

        Targets

        Cellneuropilin-2
        neuron Present
        Phenotypes
        • axon guidance
        podocyte Present
        vascularendothelial cell Present
        Phenotypes
        • regulation of angiogenesis
        Reference