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Details for messenger / hormone: VEGF-183

EndoNet ID: ENH00763

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Synonyms

  • vascular permeability factor
  • vascular endothelial growth factor A
  • VEGF-183
  • VEGF183

General information

  • VEGF183 is a cell-anchored protein that promotes increased vascular permeability but requires extracellular cleavage or release by heparin or plasmin to promote its mitogenic activity. [1]

Classification

Hormone function

  • development and growth
    • growth stimulation

    Chemical classification

    • hormone
      • genome-encoded
        • cytokines
          • PDGF/VEGF growth factor family

      Composition

      Sequence 
      APMAEGGGQ NHHEVVKFM DVYQRSYCH 
PIETLVDIF QEYPDEIEY IFKPSCVPL 
MRCGGCCND EGLECVPTE ESNITMQIM 
RIKPHQGQH IGEMSFLQH NKCECRPKK 
DRARQEKKS VRGKGKGQK RKRKKSRPC 
GPCSERRKH LFVQDPQTC KCSCKNTDS 
RCKARQLEL NERTCRCDK PRR

      Links to other resources

      UniProt P15692-3
      Ensembl ENST00000372055
      KEGG hsa:7422

      • Anatomical structure: Müllers_radial_cell_of_retina

      • Anatomical structure: heart

      Targets

      Cell
      No records found.
      Reference