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Details for messenger / hormone: NRG1-alpha2B

EndoNet ID: ENH00864

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Synonyms

  • neuregulin1-alpha2B
  • glial growth factor
  • sensory and motor neuron-derived factor
  • acetylcholine receptor-inducing activity
  • breast cancer cell differentiation factor p45
  • Heregulin
  • neu differentiation factor
  • pro-neuregulin-1, membrane-bound isoform
  • NRG1-alpha2B

General information

  • Isoform 3 is the predominant form in mesenchymal cells and in non-neuronal organs. [1]

Classification

Hormone function

  • development and growth
    • growth stimulation
      • growth inhibition
        • apoptosis

        Chemical classification

        • hormone
          • genome-encoded
            • cytokines
              • neuregulin-family

          Composition

          isoform 3, sequence

          Sequence 
          MSERKEGRG KGKGKKKER GSGKKPESA 
AGSQSPALP PRLKEMKSQ ESAAGSKLV 
LRCETSSEY SSLRFKWFK NGNELNRKN 
KPQNIKIQK KPGKSELRI NKASLADSG 
EYMCKVISK LGNDSASAN ITIVESNEI 
ITGMPASTE GAYVSSESP IRISVSTEG 
ANTSSSTST STTGTSHLV KCAEKEKTF 
CVNGGECFM VKDLSNPSR YLCKCQPGF 
TGARCTENV PMKVQNQEK AEELYQKRV 
LTITGICIA LLVVGIMCV VAYCKTKKQ 
RKKLHDRLR QSLRSERNN MMNIANGPH 
HPNPPPENV QLVNQYVSK NVISSEHIV 
EREAETSFS TSHYTSTAH HSTTVTQTP 
SHSWSNGHT ESILSESHS VIVMSSVEN 
SRHSSPTGG PRGRLNGTG GPRECNSFL 
RHARETPDS YRDSPHSER HNLIAELRR 
NKAHRSKCM QIQLSATHL RSSSIPHLG 
FIL

          Links to other resources

          UniProt Q02297-3
          Ensembl ENST00000287840
          KEGG hsa:3084

          • Anatomical structure: mesenchyme_cell

          Targets

          Cell
          No records found.
          Reference