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Details for messenger / hormone: PAI-2

EndoNet ID: ENH00939

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Synonyms

  • plasminogen activator inhibitor 2
  • placental plasminogen activator inhibitor
  • monocyte Arg-serpin
  • urokinase inhibitor
  • SERPINB2
  • PAI2
  • PLANH2
  • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2
  • serpin B2
  • PAI-2

General information

  • Function: PAI-2 is an enzyme inhibitor involved in cell differentiation, tissue regrowth and regeneration [1]
  • Inhibits urokinase-type plasminogen activator. [2]

Classification

Hormone function

  • development and growth
    • environment adaptation

    Chemical classification

    • hormone
      • genome-encoded
        • serpin family

      Composition

      PAI-2

      Sequence 
      SPTQNLFLS PWSISSTMA MVYMGSRGS 
TEDQMAKVL QFNEVGANA VTPMTPENF 
TSCGFMQQI QKGSYPDAI LQAQAADKI 
HSSFRSLSS AINASTGNY LLESVNKLF 
GEKSASFRE EYIRLCQKY YSSEPQAVD 
FLECAEEAR KKINSWVKT QTKGKIPNL 
LPEGSVDGD TRMVLVNAV YFKGKWKTP 
FEKKLNGLY PFRVNSAQR TPVQMMYLR 
EKLNIGYIE DLKAQILEL PYAGDVSMF 
LLLPDEIAD VSTGLELLE SEITYDKLN 
KWTSKDKMA EDEVEVYIP QFKLEEHYE 
LRSILRSMG MEDAFNKGR ANFSGMSER 
NDLFLSEVF HQAMVDVNE EGTEAAAGT 
GGVMTGRTG HGGPQFVAD HPFLFLIMH 
KITNCILFF GRFSSP

      Links to other resources

      UniProt P05120
      Ensembl ENST00000457692
      KEGG hsa:5055

      • Anatomical structure: monocyte

      • Anatomical structure: placenta

      • Anatomical structure: fibroblast

      • Anatomical structure: keratinocyte

      • Anatomical structure: enterochromaffin_like_cell

      • Anatomical structure: mucosa_of_gastric_wall

      • Anatomical structure: mucosa_of_small_intestine

      • Anatomical structure: mucosa_of_small_intestine

      • Anatomical structure: pyloric_part_of_stomach

      • Anatomical structure: mucosa_of_small_intestine

      • Anatomical structure: nucleus_accumbens

      • Anatomical structure: hippocampus

      • Anatomical structure: amygdaloid_body

      Targets

      Cell
      No records found.
      Reference