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Details for messenger / hormone: phenylalanine

EndoNet ID: ENH00942

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Synonyms

  • phenylalanine
  • L-phenlyalanine

General information

  • Phenylalanine is capable of increasing the maximal responsiveness to Ca2+. [1]
  • Function: phenylalanine is precursor of tyrosine and subesquently converted to other hormones (dopamine, norepinephrine, epinephrine). [2]

Classification

Hormone function

  • homeostasis
    • hormone precursor

    Chemical classification

    Links to other resources

      Targets

      CellCaSR
      astrocyte Present
      Phenotypes
      • astrocyte differentiation
      beta cell of islet of Langerhans Present
      Influences
      • ↑ insulin
      colon Present
      Phenotypes
      • colonocyte differentiation
      digestive system Present
      enteric glial cell Present
      enterochromaffin like cell Present
      epithelial cell Present
      fat cell Present
      Phenotypes
      • regulation of lipid biosynthetic process
      • inhibition of lipolysis
      G cell Present
      Influences
      • gastrin
      glial cell of central nervous system Present
      Goormaghtighs cell Present
      Influences
      • ↓ renin
      hypothalamus Present
      keratinocyte Present
      Phenotypes
      • keratinocyte differentiation
      kidney Present
      Phenotypes
      • inhibition of the reabsorption of renal mineral ions
      large intestine Present
      lymphoblast Present
      mammary gland Present
      Influences
      • ↓ PTH
      • ↓ PTHLH
      • ↑ ACTH
      monocyte Present
      Phenotypes
      • cytokine secretion
      neuron Present
      Phenotypes
      • growth of neuronal processes
      • regulation of myelination
      osteoclast Present
      Phenotypes
      • regulation of bone resorption
      osteocyte Present
      Phenotypes
      • bone cell metabolism
      pancreas Present
      Phenotypes
      • regulation of serum calcium levels
      • regulation of pancreatic ductal cells
      parathyroid gland Present
      Phenotypes
      • Familial benign hypocalciuric hypercalcemia
      Influences
      • ↓ PTH
      retinal pigment epithelium RPE Present
      thyroid gland Present
      Phenotypes
      • regulation of serum calcium levels
      • stimulation of phospholipase activity
      • inhibition of adenylate cyclase activity by G-protein signaling pathway
      • activation of MAPK cascade
      • neonatal hyperparathyroidism
      Reference