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Details for messenger / hormone: 12-oxo-LTB4

EndoNet ID: ENH00993

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  • 12-oxo-LTB4
  • 12-oxo-leukotriene B4
  • 5S-hydroxy-12-keto-6Z,8E,10E,14Z-eicosatetraenoic acid

General information

  • 12-oxo-LTB4 is a biologically less active metabolite of LTB4. [1]
  • LTB4 12-hydroxydehydrogenase catalyzes the conversion of LTB4 into 12-oxo-LTB4. [1]


Hormone function

Chemical classification

  • hormone
    • not genome-encoded
      • eicosanoids/fatty acid derivatives
        • leukotrienes


    Links to other resources

    KEGG C05949
    LIPID MAPS LMFA03020024
    LipidBank XPR3111


      brain Present
      colon Present
      heart Present
      leukocyte Present
      lung Present
      lymphoid tissue Present
      pancreas Present
      peripheral blood leukocytes Present
      placenta Present
      skeleton muscle Present
      small intestine Present
      spleen Present