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Details for messenger / hormone: lysyl-bradykinin

EndoNet ID: ENH01007

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Synonyms

  • lysyl-bradykinin
  • kallidin I
  • Ile-Ser-Bradykinin
  • alpha-2-thiol proteinase inhibitor
  • Fitzgerald factor
  • Williams-Fitzgerald-Flaujeac factor
  • high molecular weight kininogen
  • Kininogen-1
  • kallidin II

General information

  • Function: precursor for Bradykinin and also involved in many inflammatory processes. [1]

Classification

Hormone function

  • homeostasis
    • hormone precursor
    • immune response
      • activation

      Chemical classification

      • hormone
        • genome-encoded
          • kinins

        Composition

        isoform HMW

        Sequence
        KRPPGFSPF R
        UniProt P01042-1

        Links to other resources

        UniProt P01042
        Ensembl ENST00000265023
        KEGG hsa:3827
        • Anatomical structure: blood_vessel

        • Anatomical structure: continuous_vascular_endothelial_cell_of_blood_vessels_and_lymphatics

        Targets

        Cellbradykinin receptor B1bradykinin receptor B2
        endothelial cell Present
        neutrophil granulocyte Present
        Phenotypes
        • Neutrophil chemotaxis
        osteoblast Present
        Influences
        • PGE2
        • PGI2
        Present
        Influences
        • interleukin 6
        • PGE2
        • PGI2
        Reference