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Details for messenger / hormone: L-aspartate

EndoNet ID: ENH01053

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Synonyms

  • 2-aminosuccinic acid
  • L-aspartate
  • L-aspartic acid
  • aspartic acid L-form

General information

Classification

Hormone function

Chemical classification

  • hormone
    • not genome-encoded
      • amino acids
        • aspartic acids

    Composition

    Links to other resources

    KEGG C00049
    • Anatomical structure: frontal_lobe

      Influenced by:

      • 5-ht-6R
        in frontal_lobe
        • The stimulation of 5-HT6 receptor by the antagonist SB-271046 mediate a significant increase in extracellular aspartat concentration. [1]

    Targets

    CellEAAT3EAAT4GLASTGLT1
    astrocyte Present
    Phenotypes
    • excitotoxcicity
    Present
    Phenotypes
    • termination of excitatory nerve signals
    • motor neuron loss
    bergmann glia Present
    Phenotypes
    • neuronal hyperexcitability
    • termination of excitatory nerve signals
    hippocampus Present
    oligodendrocyte Present
    Phenotypes
    • excitotoxcicity
    Purkinje cell Present
    Phenotypes
    • glutamate transport
    red nucleus Present
    substantia nigra Present
    Reference