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Details for messenger / hormone: Virodhamine

EndoNet ID: ENH01083

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Synonyms

  • Virodhamine
  • O-Arachidonoyl ethanolamine
  • 2-aminoethyl (5Z,8Z,11Z,14Z)-icosa- 5,8,11,14-tetraenoate

General information

  • Opposite of the amide linkage found in anandamide. [1]

Classification

Hormone function

Chemical classification

  • hormone
    • not genome-encoded
      • eicosanoids/fatty acid derivatives
        • prostanoids

Composition

Links to other resources

  • Anatomical structure: hippocampus

    • Concentration of virodhamine was similar to anandamide. [1]

  • Anatomical structure: corpus_striatum

    • The concentration of virodhamine was lower than anandamide. [1]

  • Anatomical structure: brain_stem

    • In the periphery, especially in tissues that express the CB2 receptor, the concentration of virodhamine was higher than anandamide. [1]
    • The concentration of virodhamine was lower than anandamide. [1]

Targets

CellCB1CB2
adrenal gland Present
Influences
  • ↓ CGRP1
  • ↓ acetylcholine
  • ↓ cholecystokinin
basket cell Present
Influences
  • ↓ GABA
cerebellum Present
Influences
  • ↓ GABA
  • ↓ glutamate
cerebral cortex Present
Influences
  • ↓ serotonin
heart Present
Phenotypes
  • atrial muscle contraction
hippocampus Present
Influences
  • ↓ GABA
leukocyte Present
lung Present
pallidum Present
peripheral nerve system element Present
reticular part of substantia nigra Present
Influences
  • ↓ GABA
spinal cord Present
urinary bladder Present
Phenotypes
  • urination
Reference