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Details for messenger / hormone: Ephrin-B2

EndoNet ID: ENH01151

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Synonyms

  • HTK ligand
  • EPH-related receptor tyrosine kinase ligand 5
  • Ephrin-B2
  • EFNB2

General information

  • Eph receptors and their ephrin ligands comprise the largest family of receptor tyrosine kinases. [1]
  • Ephrin-B2 belongs to the ephrin-B class, which are transmembrane proteins. [1]

Classification

Hormone function

Chemical classification

  • hormone
    • genome-encoded
      • ephrin family

    Composition

    Ephrin-B2

    Sequence 
    IVLEPIYWN SSNSKFLPG QGLVLYPQI 
GDKLDIICP KVDSKTVGQ YEYYKVYMV 
DKDQADRCT IKKENTPLL NCAKPDQDI 
KFTIKFQEF SPNLWGLEF QKNKDYYII 
STSNGSLEG LDNQEGGVC QTRAMKILM 
KVGQDASSA GSTRNKDPT RRPELEAGT 
NGRSSTTSP FVKPNPGSS TDGNSAGHS 
GNNILGSEV ALFAGIASG CIIFIVIII 
TLVVLLLKY RRRHRKHSP QHTTTLSLS 
TLATPKRSG NNNGSEPSD IIIPLRTAD 
SVFCPHYEK VSGDYGHPV YIVQEMPPQ 
SPANIYYKV

    Links to other resources

    UniProt P52799
    Ensembl ENST00000245323
    KEGG hsa:1948

      Targets

      CellEPHB4
      placenta Present
      vascularendothelial cell Present
      Phenotypes
      • vasculogenesis
      Reference