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Details for phenotype: positive regulation of endothelial cell proliferation

EndoNet ID: ENP00015

Name

positive regulation of endothelial cell proliferation

General information

This phenotype is not pathologic

Links to other resources

GO
MeSH term 68049109

Phenotype triggers

  • normal activity of Vascular endothelial growth factor receptor 1
    in continuous_vascular_endothelial_cell_of_blood_vessels_and_lymphatics
    • VEGF promotes proliferation, migration, and survival of endothelial cells. [1]
  • normal activity of Sphingosine 1-phosphate receptor 1
    in vascularendothelial_cell
    • S1P induces proliferation of VECs. [2]
    • S1P receptor-mediated signaling plays a major regulatory role in angiogenesis. [3]
  • normal activity of Sphingosine 1-phosphate receptor 3
    in vascularendothelial_cell
    • S1P induces proliferation of VECs. [2]
    • S1P receptor-mediated signaling plays a major regulatory role in angiogenesis. [3]
Reference