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Statistic
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Details for phenotype: granulosa cell differentiation
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EndoNet ID: ENP00021
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Name
granulosa cell differentiation
General information
This phenotype is not pathologic
Links to other resources
GO
granulosa cell differentiation
Phenotype triggers
normal activity of
follitropin receptor
ui-button
in
granulosa_cell
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Follicle-stimuating hormone has a central role in ovarian folliculogenesis, particularly in regulating granulosa cell differentiation, it enhances expression of steroidogenic enzymes such as cytochrome P450 side-chain cleavage and P450 aromatase (these actions are importantly modulated by various growth factors, acting in paracrine or autocrine way).
[1]
Reference
