Details for phenotype: induction of cytokine expression

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EndoNet ID: ENP00040

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Name

induction of cytokine expression

General information

This phenotype is not pathologic

Links to other resources

GO	positive regulation of cytokine biosynthetic process

Phenotype triggers

• normal activity of Lysophosphatidic acid receptor 1 ui-button
  in vascularendothelial_cell ui-button
  • Lysophosphatidic acid induces expression of cytokines (MCP-1, IL-8, IL-1β) in vascular endothelial cells. [1]
  • Expression of inflammatory cytokines play important role in development of atherosclerosis and thrombosis. [1]

EndoNet at the Institut for Bioinformatics UMG Göttingen