Details for phenotype: suppression of interstitial fibrosis

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EndoNet ID: ENP00096

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Name

suppression of interstitial fibrosis

General information

This phenotype is not pathologic

Links to other resources

GO	negative regulation of macromolecule biosynthetic process

Phenotype triggers

• normal activity of MC1R ui-button
  in fibroblast ui-button
  • Alpha-MSH suppressed interstitial fibrosis induced by TGF-beta1 and reduced the number of vimentin and alpha-smooth muscle actin positive cells. [1]

EndoNet at the Institut for Bioinformatics UMG Göttingen