Details for phenotype: antagonizing IL-1alpha/beta ligand activity

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EndoNet ID: ENP00104

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Name

antagonizing IL-1alpha/beta ligand activity

General information

This phenotype is not pathologic

Links to other resources

GO	interleukin-1 receptor antagonist activity interleukin-1 Type I receptor antagonist activity interleukin-1 Type II receptor antagonist activity
MeSH term	68053590

Phenotype triggers

• normal activity of TNFR1 ui-button
  in hepatocyte ui-button
  • TNF induces the release of IL-1ra, which antagonizes IL-1alpha/beta ligand activity. [1]
• normal activity of TNFR2 ui-button
  in hepatocyte ui-button
  • TNF induces the release of IL-1ra, which antagonizes IL-1alpha/beta ligand activity. [1]

EndoNet at the Institut for Bioinformatics UMG Göttingen