Details for phenotype: formation of glomerular filter barrier

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EndoNet ID: ENP00127

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Name

formation of glomerular filter barrier

General information

This phenotype is not pathologic

Links to other resources

GO	regulation of glomerular filtration

Phenotype triggers

• normal activity of neuropilin 1 ui-button
  in glomerulus ui-button
  • Sema3a plays a role in the formation of the glomerular filtration barrier. [1]
  • Sema3a negatively regulates endothelial cell survival during glomerular development and a tight regulation of Sema3a dosage is necessary for normal glomerular vascularization. [1]

EndoNet at the Institut for Bioinformatics UMG Göttingen