Status
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Details for phenotype: hyperdipsia

EndoNet ID: ENP00140

Name

hyperdipsia

General information

This phenotype is not pathologic

Links to other resources

Medline Plus 001214
Disease database 10369

Phenotype triggers

  • CRF-R2
    in ventromedial_nucleus_of_hypothalamus
    • Levels of the CRF-R2 mRNA in the VMH were significantly lower in diabetic rats. Expression of CRF-R2 is mostly related to the insulin, but not to the corticosterone, status. Alterations in the brain CRF system due to insulin deficiency may contribute to the hyperdipsia in diabetes. [1]
Reference