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Statistic
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Details for phenotype: regulation of sensory perception of pain
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EndoNet ID: ENP00216
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Name
regulation of sensory perception of pain
General information
This phenotype is not pathologic
Links to other resources
GO
regulation of sensory perception of pain
MeSH term
68058748
Phenotype triggers
normal activity of
PRLR
ui-button
in
brain
ui-button
Prolactin has been shown to have analgesic effects that can be mimicked by a number of central nervous system neurotransmitters.
[1]
normal activity of
FTS receptor
ui-button
in
central_nerve_system_element
ui-button
A series of experiments showing the hyperalgesic actions of thymulin in the nervous system.
[2]
Thymulin may be acting directly or indirectly on nerve terminals of the CNS. PGE2 might be a key mediator in these actions.
[2]
The attenuation of hyperalgesia by high doses of thymulin involve the downregulation of proinflammatory cytokines.
[2]
Reference