Details for phenotype: negative regulation of interferon-gamma and interleukin-4 production

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EndoNet ID: ENP00266

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Name

negative regulation of interferon-gamma and interleukin-4 production

General information

This phenotype is not pathologic

Links to other resources

GO	negative regulation of interferon-gamma production negative regulation of interleukin-4 production
MeSH term	68016207

Phenotype triggers

• normal activity of Sphingosine 1-phosphate receptor 4 ui-button
  in T-lymphocyte ui-button
  • Signalling through S1PR4 in CD4+ T cells suppresses production of both cytokines, IFNgamma and IL-4, equally. [1]

EndoNet at the Institut for Bioinformatics UMG Göttingen