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Statistic
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Details for phenotype: myelin formation in the central nervous system
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EndoNet ID: ENP00302
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Name
myelin formation in the central nervous system
General information
This phenotype is not pathologic
Links to other resources
GO
myelin formation in the central nervous system
MeSH term
68009186
Phenotype triggers
normal activity of
Lysophosphatidic acid receptor 1
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in
oligodendrocyte
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A significant role for LPA signaling in myelination was suggested by the Lpar1 gene expression pattern that spatially and temporally correlated with oligodendrocyte myelination.
[1]
LPA has a positive effect on process formation and myelin basic protein production in oligodendrocytes.
[2]
Reference
