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Statistic
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Details for phenotype: gastrointestinal cancer
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EndoNet ID: ENP00332
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Name
gastrointestinal cancer
General information
This phenotype is pathologic
Links to other resources
GO
positive regulation of organ growth
MeSH term
68005770
Phenotype triggers
more activity (high ligand concentration, overexpression) of
Lysophosphatidic acid receptor 2
ui-button
in
digestive_system
ui-button
LPA is implicated in the progression of gastrointestinal cancers. LPA stimulates proliferation, migration, and invasion primarily through the activation of LPA2.
[1]
more activity (high ligand concentration, overexpression) of
Lysophosphatidic acid receptor 1
ui-button
in
digestive_system
ui-button
LPA is implicated in the progression of gastrointestinal cancers. LPA stimulates proliferation, migration, and invasion primarily through the activation of LPA1.
[2]
Reference
