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Statistic
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Details for phenotype: negative regulation of fat cell differentiation
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EndoNet ID: ENP00337
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Name
negative regulation of fat cell differentiation
General information
This phenotype is not pathologic
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GO
negative regulation of fat cell differentiation
MeSH term
68002454
Phenotype triggers
normal activity of
Lysophosphatidic acid receptor 1
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in
preadipocyte
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LPA1 signaling appears to be antiadipogenic because stimulation of LPA1 signaling inhibits the differentiation of preadipocytes. This inhibitory effect is the result of the downregulation of PPARγ2.
[1]
Reference