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Statistic
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Details for phenotype: negative regulation of progesterone biosynthetic process
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EndoNet ID: ENP00349
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Name
negative regulation of progesterone biosynthetic process
General information
This phenotype is not pathologic
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GO
negative regulation of progesterone biosynthetic process
MeSH term
68011374
Phenotype triggers
normal activity of
Lysophosphatidic acid receptor 2
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in
corpus_luteum
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In luteal cells temporally coexpressing endogenous LPA2 receptor during mid-cycle, LPA inhibits agonist-stimulated progesterone production at a step distal to the cyclic AMP formation and before the steroid synthesis in mitochondria.
[1]
Reference