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Details for phenotype: negative regulation of progesterone biosynthetic process

EndoNet ID: ENP00349

Name

negative regulation of progesterone biosynthetic process

General information

This phenotype is not pathologic

Links to other resources

GO
MeSH term 68011374

Phenotype triggers

  • normal activity of Lysophosphatidic acid receptor 2
    in corpus_luteum
    • In luteal cells temporally coexpressing endogenous LPA2 receptor during mid-cycle, LPA inhibits agonist-stimulated progesterone production at a step distal to the cyclic AMP formation and before the steroid synthesis in mitochondria. [1]
Reference