Details for phenotype: activation of malignant B cells

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EndoNet ID: ENP00445

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Name

activation of malignant B cells

General information

This phenotype is pathologic

Links to other resources

GO	positive regulation of B cell activation
MeSH term	68008213

Phenotype triggers

• more activity (high ligand concentration, overexpression) of PRLR ui-button
  in lymphocyte ui-button
  • Prolactin is thought to activate malignant B lymphocytes. [1]
  • Prolactin has a role in the growth of some cancers of lymphoid origin in rats. [2]

EndoNet at the Institut for Bioinformatics UMG Göttingen