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Statistic
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Details for phenotype: rheumatoid arthritis
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EndoNet ID: ENP00449
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Name
rheumatoid arthritis
General information
This phenotype is pathologic
Links to other resources
GO
regulation of inflammatory response
OMIM
180300
Medline Plus
000431
MeSH term
D001172
Disease database
11506
Phenotype triggers
more activity (high ligand concentration, overexpression) of
PRLR
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in
immune_system
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Prolactin has been shown to be increases and to effect a number of autoimmune states, such as rheumatoid arthritis.
[1]
Children with antinuclear antibodies seropositive juvenile rheumatoid arthritis have elevated serum levels of the immunostimulatory hormone prolactin.
[1]
Reference
