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Details for phenotype: Hyperthyroidism
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EndoNet ID: ENP00492
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Name
Hyperthyroidism
General information
This phenotype is pathologic
Markedly increased appetite is considered to be a clinical feature of hyperthyroidism, and hyperphagia and enhanced energy intake have indeed been formally documented in thyrotoxicosis.
[1]
Links to other resources
GO
thyroid hormone generation
Medline Plus
000356
MeSH term
D006980
Disease database
6348
Phenotype triggers
more activity (high ligand concentration, overexpression) of
thyroid hormone receptor
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in
thyroid_gland
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Resistance to thyroid hormone is an uncommon disorder, characterized by elevated circulating thyroid hormones with nonsuppressed thyrotropin levels, reflecting resistance within the hypothalamic-pituitary-thyroid axis but variable refractoriness to hormone action in peripheral tissues.
[2]
Reference
