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Statistic
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Details for phenotype: positive regulation of macrophage derived foam cell
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EndoNet ID: ENP00550
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Name
positive regulation of macrophage derived foam cell
General information
This phenotype is not pathologic
Links to other resources
GO
positive regulation of macrophage derived foam cell differentiation
MeSH term
68005487
Phenotype triggers
normal activity of
vitronectin receptor
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in
macrophage
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AlphaVbeta3 integrin regulates macrophage functional maturation into foam cells in a persistent manner
[1]
normal activity of
thrombospondin receptor
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in
monocyte
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CD36 binds LDL that has been exposed to "minimally" oxidizing conditions.
[2]
CD36 has a critical role in monocyte/macrophage foam cell formation and atherosclerosis.
[3]
Reference
