Status
Please wait ...
EndoNet
The information resource about the endocrine network in human.
Search
Search a component
Browse
Browse pathways
Browse hormones
Browse hormones functions
Browse hormone classification
Browse receptors
Network
Load network
Path analysis
Process network
Help
Help
Statistic
About
Details for phenotype: promotion of mesenchymal cell differentiation
Top
General information
Triggers
Toolbox
Click to access the toolbox
Top
General information
Triggers
Toolbox
Click to access the toolbox
EndoNet ID: ENP00606
Add to network
Name
promotion of mesenchymal cell differentiation
General information
This phenotype is not pathologic
Links to other resources
GO
mesenchymal cell differentiation
MeSH term
68002454
Phenotype triggers
normal activity of
Sphingosine 1-phosphate receptor 2
ui-button
in
adipose_tissue
ui-button
S1P2 appears to be, by pharmacological inhibition, the most important receptor for transmitting the myogenic signal brought about by S1P.
[1]
S1P promotes differentiation of adipose tissue-derived mesenchymal stem cells towards smooth muscle cells, by enhancing the expression of myogenic marker proteins and by inducing the onset of ionic currents which are characteristic of myogenic phenotype.
[1]
Reference
