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Details for phenotype: positive regulation of cell-matrix adhesion

EndoNet ID: ENP00642


positive regulation of cell-matrix adhesion

General information

This phenotype is not pathologic

Links to other resources

MeSH term 68055166

Phenotype triggers

  • normal activity of LRP5
    in lipocyte_of_liver
    • Cultured rat hepatic stellate cells (HSCs) produce CTGF which is a cell adhesion factor for activated HSCs. LRP is a receptor for CTGF. [1]
    • LRP is utilized by HSCs for binding to CTGF and so this cell surface molecule may be involved in mediating CTGF activity or adhesive signaling during the activation process. [1]