Details for phenotype: colonocyte differentiation

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EndoNet ID: ENP00673

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Name

colonocyte differentiation

General information

This phenotype is not pathologic

Links to other resources

Phenotype triggers

• normal activity of CaSR ui-button
  in colon ui-button
  • The CaSR plays an important role in the proliferation and differentiation of colonocytes. [1]
  • The CaSR promotes the expression of E-cadherin and suppresses the activation of ß-catenin/ TCF factor, therby regulating the differentiation of colonic epithelial cells. [2]

EndoNet at the Institut for Bioinformatics UMG Göttingen