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Details for phenotype: colonocyte differentiation

EndoNet ID: ENP00673


colonocyte differentiation

General information

This phenotype is not pathologic

Links to other resources

Phenotype triggers

  • normal activity of CaSR
    in colon
    • The CaSR plays an important role in the proliferation and differentiation of colonocytes. [1]
    • The CaSR promotes the expression of E-cadherin and suppresses the activation of ß-catenin/ TCF factor, therby regulating the differentiation of colonic epithelial cells. [2]