Details for phenotype: excitotoxcicity

• Top
• General information
• Triggers
• Toolbox
  Click to access the toolbox

• Top
• General information
• Triggers
• Toolbox
  Click to access the toolbox

EndoNet ID: ENP00674

Add to network

Name

excitotoxcicity

General information

This phenotype is pathologic

Links to other resources

Phenotype triggers

• GLAST ui-button
  in oligodendrocyte ui-button
  • The uptake of glutamate from the synaptic cleft by GLAST is crucial for the termination of excitatory neurotransmission. thereby preventing pathologic excitotoxicity. [1]
• GLAST ui-button
  in astrocyte ui-button
  • The glutamate receptor GLAST maintains low synaptic glutamate levels to terminate glutamate signaling and prevent pathologic excitotoxicity. [2]

EndoNet at the Institut for Bioinformatics UMG Göttingen